When it comes to sneaker customization, those of us who don't have the necessary artistic abilities have to settle for NikeiD- which is a dope tool for sneakerheads who want to create a pair of kicks that aren't the same as what everybody has.
If you want to take it a step further, there's NikeLab's exclusive Bespoke Program which is on a completely different level. In short, NikeLab's 21 Mercer location will hook you up with a designer, review the complete range of material options, and build you a 1-of-1 sneaker.
Scheduling an appointment at a NikeLab location and customizing your own pair of Bespoke kicks with premium materials will run you about $800, but you're guaranteed to come away with something that's one of a kind.
For instance, this Coogi Air Force 1 created by @Rockyxu which was actually constructed using an old Coogi sweater.